Ana Graham studied at the Núcleo de Estudios Teatrales. She is the artistic director and founder of Por Piedad Teatro Foundation in New York City and Por Piedad Teatro Producciones A.C. in Mexico City, where she has developed most of her career as an actress, producer, translator, and costume designer. Some of her works include Ladies and Gents by Paul Walker; Playing the Victim by the Presnyakov Brothers; Psychosis 4.48 by Sarah Kane for which she was nominated as Best Actress by APT, ; Crave and Blasted also by Sarah Kane and for which she was awarded as Best Actress and Best Translator by APT; The Country by Martin Crimp; Some Explicit Polaroids by Mark Ravenhill for which she was nominated as Best Supporting Actress by APT; Grace and Glory by Tom Ziegler, for which she was awarded as Best Young Actress by APT; and Interiors by Woody Allen. Outside Por Piedad she is remembered by her preformance in Hedda Gabler by Hernik Ibsen, Equus by Peter Shaffer and Sexual Perversity in Chicago by David Mamet. In film she starred in Mezcal, a film by Ignacio Ortiz, for which she was nominated for an Ariel as Best Actress and in Cuento de Hadas para Dormir Cocodrilos. In 2003 she held the annual grant for performing artist from Mexico's National Found for the Arts.